Endocrine Abstracts

Introduction: Hereditary phaeochromocytoma (PCC) and paraganglioma (PGL) account for 30–35% of cases and have some clinically relevant peculiarities.Material and methods: Retrospective, unicentric cohort study that included all genotyped patients (n=36, 27 with PCC and 9 with PGL) diagnosed at Hospital Clínico San Carlos (Madrid) between 1984 and 2013; 33% were germline mutation carriers (25% pseudohypoxic [PH] phenotype, 75% MAP-kinas...

Introduction: Hereditary Medullary Thyroid Cancer (MTC) accounts for 20–30% of cases and has some clinically relevant peculiarities.Material and methods: Retrospective, unicentric cohort study that included all genotyped patients with MTC (n=48) diagnosed at Hospital Clínico San Carlos (Madrid) between 1984–2013; 42% were germline mutation carriers (45% moderate risk (category MOD), 45% high risk (category H), 10% highest risk (ca...

Introduction: Hyponatraemia is the most common electrolytic disorder in clinical practice. We designed a protocol, based on the latest consensus statements and adapted to our Hospital, for the use of 3% hypertonic saline solution (HSS) in patients with hyponatraemia.Material and methods: Unicentric observational study of a case series. We collected data from 14 adult patients with severe hyponatraemia (serum sodium [SNa] <125 mmol/l) and mild-moderat...